RT Journal Article
SR Electronic
T1 Side effects of drug treatments for gastro-oesophageal reflux disease: current controversies
JF Frontline Gastroenterology
JO Frontline Gastroenterol
FD BMJ Publishing Group Ltd
SP 45
OP 49
DO 10.1136/flgastro-2019-101386
VO 13
IS 1
A1 Dhar, Anjan
A1 Maw, Frances
A1 Dallal, Helen Jane
A1 Attwood, Stephen
YR 2022
UL http://fg.bmj.com/content/13/1/45.abstract
AB The two main drugs used in the treatment of gastro-oesophageal reflux disease are proton pump inhibitors and histamine-2 receptor antagonists and both these agents have been implicated in a number of adverse effects, leading to considerable controversies related to their long-term use. This paper is aimed at a critical review of the published literature and the clinical significance of these reported side effects, most of which are associations rather than causal.